nadph oxidase การใช้

• This process is counterbalanced by NADPH oxidase inhibitors, and by antioxidants.
• Phagocytes possess a superoxide-producing NADPH oxidase enzyme complex.
• NADPH oxidase is a major cause of atherosclerosis, and NADPH oxidase inhibitors may reverse atherosclerosis.
• NADPH oxidase is a major cause of atherosclerosis, and NADPH oxidase inhibitors may reverse atherosclerosis.
• The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase.
• Moreover, PFKL regulates NADPH oxidase activity through the pentose phosphate pathway and according to NADPH levels.
• It has also been identified to inhibit NADPH oxidase ( NOX1 ) NADPH _ oxidase in lung homogenate.
• Absence of NADPH oxidase will prevent the formation of reactive oxygen species and will result in chronic granulomatous disease.
• This domain was first found in P40phox and p47phox domains of NADPH oxidase ( phox stands for phagocytic oxidase ).
• Human white blood cells use enzymes such as NADPH oxidase to generate superoxide and other reactive oxygen species to kill bacteria.
• Neutrophil cytosolic factor 2 is an essential to NADPH oxidase complex which in turn produces superoxides in return to microbial infection.
• To combat infections, immune cells use NADPH oxidase to reduce O 2 to oxygen free radical and then H 2 O 2.
• When there is an NADPH oxidase defect, the phagocyte is unable to make reactive oxygen species or radicals required for bacterial killing.
• In phagocytes, superoxide is produced in large quantities by the enzyme NADPH oxidase for use in oxygen-dependent killing mechanisms of invading pathogens.
• NADPH oxidase generates superoxide by transferring electrons from NADPH inside the cell across the fungi, or it can be produced outside of the cell.
• Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW : Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
• Defects in one of the four essential subunits of phagocyte NADPH oxidase ( PHOX ) can all cause CGD of varying severity, dependent on the defect.
• In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles.
• Apocynin was used to determine whether ionic activation due to proton flux across the membrane of renal medulla cells was coupled to NADPH oxidase production of superoxide.
• However, it was instead discovered that recombinant AIF that do not have the last 100 N-terminal amino acids have limited NADP and NADPH oxidase activity.